9/3/2023 0 Comments Metaz application![]() The benefits and risks of use should be considered in pregnant patients In animal studies of pregnancy, some fetal toxic effects were seen at or above the maximum recommended human dose, though rodents are more sensitive to these effects than humans. Symptoms of chronic overuse may present as hypercorticism and adrenal suppression, and patients may not require any more treatment than monitoring. Overdose with a mometasone furoate inhaler may occur with chronic overuse. Metaz also reduces inflammation by blocking transcription factors such as activator-protein-1 and nuclear factor kappa B (NF-kappaB). Once at the nucleus, receptors dimerize and bind to a DNA sequence known as the glucocorticoid response element which either increases expression of anti-inflammatory molecules or inhibits expression of pro-inflammatory molecules (such as interleukins 4 and 5). Metaz binding to a glucocorticoid receptor causes conformational changes in the receptor, separation from chaperones, and the receptor moves to the nucleus. Metaz has a particularly high receptor affinity compare to other corticosteroids, 22 times higher than that of dexamethasone. There is also evidence of inhibition of histamine, leukotrienes, and cytokines.Ĭorticosteroids diffuse across cell membranes into the cytosol of cells where they bind to glucocorticoid receptors to produce their activity. In asthma, mometasone is believed to inhibit mast cells, eosinophils, basophils, and lymphocytes. Metaz is also used to associated treatment for these conditions: Allergic Rhinitis (AR), Asthma, Dermatitis, Dermatitis, Eczematous caused by superficial Fungal skin infection, Moderate to Severe Plaque Psoriasis, Polyps, Nasal, Pruritus, Psoriasis, Psoriasis, Moderate to Severe, Seasonal Allergies, Skin Diseases, Eczematous, Skin Infections ![]() The ointment is indicated for symptomatic treatment of dermatitis and pruritis in patients ≥2 years. The nasal spray is indicated for treating nasal symptoms of allergic rhinitis in patients ≥2 years, treating symptoms of nasal congestion from seasonal allergic rhinitis in patients ≥2 years, treating nasal polyps in patients ≥18 years, and prophylaxis of seasonal allergic rhinitis in patients ≥12 years. The inhaler is indicated for prophylaxis of asthma in patients ≥4 years. There are 3 formulations of mometasone furoate with various indications. Contact us today to learn more about our comprehensive selection of pharmacy products and how we can support your ongoing medical care.Metaz is a corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. We are committed to ensuring that our patients have access to the highest quality pharmacy products available. Our knowledgeable pharmacists are available to help our patients find the right medical supplies for their needs and to answer any questions they may have about their use. That's why we offer a wide range of medical supplies, including wound care products, diabetic supplies, and more. Our knowledgeable pharmacists are available to help our patients find the right products for their needs and to answer any questions they may have about over-the-counter medication or supplements.Īt Second Medic, we understand that medical supplies can also play an important role in our patients' health and wellbeing. Our pharmacy is stocked with a comprehensive selection of products to meet the diverse needs of our patients, including vitamins, pain relievers, allergy medication, and more. In addition to prescription medication, we also offer a wide range of over-the-counter medication and supplements to support our patients' overall health and wellbeing. We also offer prescription refill reminders and prescription delivery services to make it easier for our patients to manage their medication regimen. Our experienced pharmacists work closely with our patients' physicians to ensure that they receive the right medication at the right dosage, and they are available to answer any questions or concerns that our patients may have about their medication. Our prescription medication products are available to patients who have been prescribed medication by their physician. ![]() Each of our pharmacy products is carefully selected to meet the diverse needs of our patients, and we are dedicated to providing personalized and compassionate care to ensure that our patients receive the right medication at the right dosage. At Second Medic, we offer a wide range of high-quality pharmacy products to support our patients' health and wellbeing.
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